Analysis of Nicotine Metabolites in Hair and Nails Using QuEChERS Method Followed by Liquid Chromatography–Tandem Mass Spectrometry
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چکیده
منابع مشابه
Determination of methamphetamine and its metabolites incorporated in hair by column-switching liquid chromatography-mass spectrometry.
An automated column-switching liquid chromatographic-electrospray ionization-mass spectrometric (LC-ESI-MS) method has been established for the determination of methamphetamine (MA) and its metabolites, amphetamine (AP), and p-hydroxymethamphetamine (p-OH-MA) in hair. The combination of an N-vinylacetamide-containing hydrophilic polymer online extraction column, an SCX semi-micro LC column, and...
متن کاملSimultaneous and sensitive measurement of anabasine, nicotine, and nicotine metabolites in human urine by liquid chromatography-tandem mass spectrometry.
BACKGROUND Determination of nicotine metabolism/pharmacokinetics provides a useful tool for estimating uptake of nicotine and tobacco-related toxicants, for understanding the pharmacologic effects of nicotine and nicotine addiction, and for optimizing nicotine dependency treatment. METHODS We developed a sensitive method for analysis of nicotine and five major nicotine metabolites, including ...
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Introduction: In recent years, due to the increase in the use of pesticides in agricultural products and its entry into the human food chain, there has been an increase in concerns about the health of food among people. Therefore, the purpose of conducting this research is to validate the analysis method. 25 pesticide residues in rice using LC-MS/MS. Methods: In this research, a simultaneous an...
متن کاملNicotine staining of the hair and nails.
CLINICAL CHALLENGE Patients are not always forthcoming about their tobacco use. Smoking and other forms of tobacco use have serious health consequences, and many dermatologic diseases and treatments are negatively affected by tobacco exposure. When a patient does not disclose their full tobacco history, the dermatologist can miss a valuable opportunity to counsel the patient on tobacco cessatio...
متن کاملCombined Liquid Chromatography–Tandem Mass Spectrometry Analysis of Progesterone Metabolites
Progesterone has a number of important functions throughout the human body. While the roles of progesterone are well known, the possible actions and implications of progesterone metabolites in different tissues remain to be determined. There is a growing body of evidence that these metabolites are not inactive, but can have significant biological effects, as anesthetics, anxiolytics and anticon...
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ژورنال
عنوان ژورنال: Molecules
سال: 2020
ISSN: 1420-3049
DOI: 10.3390/molecules25081763